Fluorescent silica particles

  • are produced by hydrolysis of orthosilicates and related compounds,

  • contain a high amount of covalently bound fluorescence dye in the silica matrix and are extremely stable in organic solvents and buffers (No toxic effects come from the covalently bound fluorescence dyes.),

  • are available with red fluorescence ( -red, excitation: 569 nm, emission: 585 nm), green fluorescence (-green, excitation: 485 nm, emission: 510 nm) and blue fluorescence (-blue, excitation: 354 nm, emission: 450 nm),  

  • have a hydrophilic surface with terminal Si-OH-bonds,

  • are designed with the surface functionalities NH2 and COOH for the covalent binding of proteins, antibodies, oligonucleotides, enzymes or other molecules,

  • are monodisperse and nonporous in the size range of 30 nm to 1,5 µm with a density of 2.0 g/cm³,

  • have broader size distributions in the area of the porous silica particles with adjusted diameters between 3 and 20 microns and a density of 1.8 g/cm³,

  • particles ≥ 200 nm can easily be separated by simple sedimentation or centrifugation,

  • particles < 200 nm can be separated by ultracentrifugation or washed by SEC or ultrafiltration/dialysis,

  • are often applied for detection purposes (flow cytometry, membrane checks, flow investigations),

  • particles with special fluorescence dyes can be made on customers request.