Red-fluorescent crosslinked magnetic dextran nanoparticles

-red particles combine separation and detection purposes. They show a red fluorescence (excitation: 552 nm, emission: 580 nm).
The 100 nm   -red particles are prepared by precipitation of iron oxide in the presence of dextran. They consist of about 80-90% (w/w) iron oxide in a matrix of crosslinked dextran (40.000 Da) and can not be separated with a conventional permanent magnet but in a high gradient magnetic field.
The 300 nm  -red are prepared by the core-shell method. They consist of about 80-90% (w/w) iron oxide in a matrix of crosslinked dextran (40.000 Da) and can easily be separated with conventional permanent magnets.
The -red particles are available with a plain surface or with amino groups on the surface for the covalent binding of proteins, antibodies or other molecules.