Silica-fortified magnetic dextran nanoparticles
are prepared via the core-shell method with a core of magnetite and a dextran shell with a simultaneous cross-linking of the dextran strands by silica nanostructures,
have a diameter of 250 nm and a magnetite content of 75-80%,
can easily be separated with a conventional permanent magnet,
are designed with the surface functionalities OH (plain), NH2 and COOH for the covalent binding of proteins, antibodies or other molecules,
are available with the hydrophobic octadecyl (C18) surface especially for nucleic acid separation.